This paper compares power electronic systems (PES) concerning their suitability for system integration in the machine housing of variable speed drives (VSD). The entire PES consisting of power semiconductors, heatsink, line filter, DC-Link capacitor and clamp circuit is investigated with respect to the required volume and power losses. The following PES topologies are analyzed: Matrix Converters (MXC), Two-Level Voltage-Source- Converters (2L-VSC), Three-Level Neutral Point Clamped-VSC (3L-NPC-VSC) and Three-Level TType NPC-VSC (3L-TNPC-VSC). The PES are investigated for a mechanical power range Pmech from 10 to 40 kW with state-of-the-art power semiconductor technologies including silicon (Si) and silicon carbide (SiC) devices. Based on the investigation results, the best suited combination of converter topology and power semiconductor type is given.